Frontiers Advances in the study of acetaminophen induced liver injury Acetaminophen, ethanol and other co ingestions ScienceDirect Sex differences in glutathione metabolism and acetaminophen toxicity Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses Smith 2013 The FASEB Journal Wiley Online Library Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which